Bring out those headphones for the best possible experience!
Unlike traditional video calls, we may be playing music, videos, and you will spend very little time "muted." In order to keep the media from echoing for all the other players, everyone should use headphones. Air pods and earbuds are fine. Cheap airline headphones are fine. Your kid's unicorn headphones are fine.
All this being said, headphones are not absolutely critical. When in a group video conversation or on a team, you'll want to turn your music all the way down or mute it.
Tip: Look in the righthand side for the volume slider/mute button.